Blue Light: Interview with Prof. Giuseppe Querques, Italy
Prof. Giuseppe Querques
Points de Vue, the International Review of Ophthalmic Optics
Age-related macular degeneration is a premature aging of the retina.
Several factors come into play in this multifactorial disease, including those with an inflammatory effect, as well as the genetic background.
Blue-violet light is mainly responsible for the process of apoptosis as it causes a photochemical phenomenon that leads to the overloading of retinal pigment epithelium cells with an extremely toxic component, named lipofuscin.
We can try to reduce the apoptotic process by adopting a combined approach.
Large steps have been taken to demonstrate the negative effect of blue-violet light on retinal cells in the macula and thus on the retinal pigment epithelium and photoreceptors.
Studies have evidenced that light wavelengths from 415 to 455 nanometers are particularly harmful.
Professor Giuseppe Querques is Associate Professor and Head of Medical Retina & Imaging Unit at University Vita-Salute, Milan, Italy.