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RESEARCH STUDY

RESEARCH

IMI - Clinical Myopia Control Trials and Instrumentation Report

AUTHOR:

James S. Wolffsohn; Pete S. Kollbaum; David A. Berntsen; David A. Atchison; Alexandra Benavente; Arthur Bradley; Hetal Buckhurst; Michael Collins; Takashi Fujikado; Takahiro Hiraoka; Masakazu Hirota; Debbie Jones; Nicola S. Logan; Linda Lundström; Hidemasa Torii; Scott A. Read; Kovin Naidoo

SPONSOR/INSTITUTION:

International Myopia Institute, Brien Holden Vision Institute, Carl Zeiss Vision, Coopervision, Essilor, Alcon, and Vision Impact Institute

YEAR PUBLISHED:

2019

PUBLICATION:

Investigative Ophthalmology & Visual Science, Arvo Journal

KEY HIGHLIGHTS:

  • The evidence-basis based on existing myopia control trials along with the supporting academic literature were reviewed; this informed recommendations on the outcomes suggested from clinical trials aimed at slowing myopia progression to show the effectiveness of treatments and the impact on patients.

  • These outcomes were classified as primary (refractive error and/or axial length), secondary (patient reported outcomes and treatment compliance), and exploratory (peripheral refraction, accommodative changes, ocular alignment, pupil size, outdoor activity/lighting levels, anterior and posterior segment imaging, and tissue biomechanics).

  • The currently available instrumentation, which the literature has shown to best achieve the primary and secondary outcomes, was reviewed and critiqued. Issues relating to study design and patient selection were also identified.

  • These findings and consensus from the International Myopia Institute members led to final recommendations to inform future instrumentation development and to guide clinical trial protocols.

To access the Clinical Summaries in all languages, click here: https://myopiainstitute.org/imi-white-papers/